Technical Report: Medicine Selection and Use Technical Brief

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South Africa remains at the center of the worldwide AIDS epidemic, with an estimated 5.6 million people living with the disease. In addition, the country has the third-highest burden of tuberculosis (TB) internationally. 1 South Africa’s unique disease burden shapes the country’s national health priorities, health system design, and health funding structures. The limited funds for medicines and medicine-related health technologies available under the National Health Insurance (NHI) fund must be allocated according to an evidence-based approach in order to provide the best quality of healthcare to all South Africans.